Abstract

SEVILLA PAZ SOLDAN, Ricardo; ZALLES CUET, Lourdes  and  SEVILLA ENCINA, Gerard. Effect of a monitoring scheme and nutritional treatment in severely malnourished children, optimal ap-proach to cell signaling. Gac Med Bol [online]. 2012, vol.35, n.2, pp.62-66. ISSN 1012-2966.

Objectives: communication, cell signaling, metabolism, growth, immunity, needs to be considered in child malnutrition. there is no nutritional preparation / remedy to cure the child, a set of actions achieve therapeutic success. the study was conducted to determine the effect of a nutritional scheme. Methods: from 1200 on the CRIN recovered children, 44 severely malnourished children were admitted to the study. Criteria: P / T < 2 D / E, and / or edema, 6 months - 5 years, hemoglobin < 8g/dl, written parental consent. Excluded: disabled: cerebral palsy, complicated with sepsis. Lymphocytes was counted with monoclonal antibodies by indirect immunofluorescence: CD3, CD4, CD8, CD20, CD1a, CD71A transferrin receptors, phagocytosis with nitro blue tetrazolium. Were determined: CRP, IL-1, IL-6; FNTa by Elisa. Cianmetaglobin hemoglobin. Transferrin, albumin turbimetria. Cultures were performed, total lymphocyte count, thymic ultra-sound, anthropometry, nutritional balance, psychomotor development, for three weeks. Powered by multidiscliplinary team. Intake was monitored: Protein, calories, 13 vitamins, 7 minerals. We performed the following statistical analysis: Predictions, Pearson correlations, t student with SPSS 19. Significance: p < 0.05. Results: children nutritionally improved, infections ceased, immature populations CD1 A decreased CD71, CD3, CD4, CD20 improved, CD8 normal. IL-1, IL-6; FTa, phagocytes declined. Hb levels, RTL, improved development. Equations were balanced nutrition. To find significant correlations between variables. Conclusions: strategies related to a cell living environment, lifestyle itself around the child, nutrient supply, constant interaction. They are essential for cell function harmony and full recovery of the child.

Keywords : cells; nutrients; receptors; immunity; malnutrition; recovery.