Abstract

TORREZ SALAZAR, Jeanneth; TORREZ SALAZAR, Jandira T.; ESPINOZA DAVILA, Elvy  and  GUTIERREZ MENDEZ, José. Graft survival in kidney transplant patients in a hospital center. Gac Med Bol [online]. 2011, vol.34, n.2, pp.87-90. ISSN 1012-2966.

Objectives: to evaluate renal graft survival and associated risk factors that contribute directly and indirectly to the deterioration of renal function during follow-up at 1, 5 and 10 years performed the transplant, patients who were transplanted at Hospital Obrero N°2 C.N.S since 1996 to 2006 and identify the etiology of chronic kidney disease (CKD), immunological risk, time on dialysis at transplant, events of rejection, immunosuppressive treatment and causes of mortality. Methods: a retrospective, cross-sectional and descriptive.The data collection instrument was a form of data collection. We studied 35 patients transplanted at Hospital Obreo N°2 C.N.S Results: the most frequent etiology was the Unknown nephropathy, reaching a graft survival of 97% living donor peryear, 77% at 5 years and 37% at 10 years. The DVR, with two haplotypes, early transplant, dialysis <12 months, acute rejection or non, are associated with longer survival of the graft. With regard to immunosuppressive therapy, identifies the acute and chronic rejection scheme is related to Cyclosporine / Azathioprine / prednisone (CYA / AZA / PDN) and chronic rejection only with the scheme cyclosporine / mycophenolate / prednisone (CYA / MMF / PDN). We identified 6 patients who died with functioning graft, being sepsis the most frequent cause. Conclusions: we performed 35 transplants. is clear that the most common etiology of CKD in the transplant patient group is Unknown nephropathy, followed by glomerulonephritis and diabetic nephropathy. Note that the kidney biopsies to identify the etiology of patients was limited because most dialysis entered with uremia.

Keywords : kidney transplantation; graft survival; Bolivia.

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