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Gaceta Médica Boliviana

Print version ISSN 1012-2966On-line version ISSN 2227-3662


ARANDIA VALDEZ, Rubén; CAMACHO ARNEZ, Mery  and  FERNANDEZ RIOS, Edgar. Enteral probiotics to reduce the incidence and severity of necrotizing enterocolitis in preterm infants with very low weight Center of Neonatal Intensive Care  Hospital Materno Infantil "Germán Urquidi". Gac Med Bol [online]. 2010, vol.33, n.2, pp.26-29. ISSN 1012-2966.

At birth the neonatal intestinal tract is sterile, as the human intestine is exposed to the contaminated environment it is colonized by nonpathogenic bacteria, favorable in the majority as lactobacillus and bifidobacteria. In contrast, the preterm intestine tends to be colonized by pathogenic micro-organisms, predominantly coliforms, enterococci and bacteroides, species that increase the risk of developing necrotizing enterocolitis. This work have the objective of assess the effectiveness and efficiency of enteral probiotics to prevent necrotizing enterocolitis in preterm new born. We conducted a prospective controlled study of blinding and randomized. For this study were chosen pretermos new-borns of very low birth weight. Were distributed patients in two groups. Children in the study group received probiotic milk 2 times a day until they were discharged, only the control children received milk without probiotics; evolutionary parameters being investigated the presence of enterocolitis and death. 68 preterm infants participated in very low birth weight, 34 in study group and 34 in control group, clinical and deve-lopmental variables were significant differences between groups. The incidence of necrotizing enterocolitis was less in the study group (2 / 34 versus 16/34) and there were 4 cases of severe necrotizing enterocolitis (Bell stage III) in the control group versus none in the study group.

Keywords : prematurity; enterocolitis; probioticos.

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