Abstract

MERINO ALMARAZ, Vania Nohelia; LOZANO BELTRAN, Daniel Franz  and  TORRICO, Faustino. Factors influencing adherence to supplementation with iron sulfate during pregnancy. Gac Med Bol [online]. 2010, vol.33, n.2, pp.21-25. ISSN 1012-2966.

The use of ferrous sulfate in the prevention of anemia during pregnancy is free and required for patients by the Universal Maternal Child Insurance (SUMI), however, the level of drug adherence at prenatal checkups and the factors influencing non-adherence are unknown. The purpose of this study is the identification of these factors. We present a case-control study of 182 women in the immediate postpartum period in the "German Urquidi Maternal Child Hospital" from August to September 2009, of which 135 patients were categorized with poor adherence (cases) and 47 women with good adherence (controls). We analyzed epidemiological factors, therapy-dependent factors, adverse effects, physician-patient relationships, and patient perception / attitudes towards medication. Results: The drug adherence was 26%. Incomplete primary education (OR = 2.12, p = 0.0355), presence of nausea (OR 3.05, p = 0.02) and the long time of treatment (OR 2.46, p=0.011) demonstrated a negative effect on drug adherence. Factors associated with good drug adherence were a strict regular dosing schedule (OR = 0.49, p = 0.01) and a trusting relationship with the prescribing physician (OR 0.34, p = 0.046). To achieve a good drug adherence should improve the relation doctor - patients and explanations about the drug's effects by level of education of the patient.

Keywords : Drug adherence; ferrous sulfate; anemia in pregnancy.

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