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Gaceta Médica Boliviana

Print version ISSN 1012-2966On-line version ISSN 2227-3662


BRANEZ GARCIA, Cristian Alexander; PARDO NOVAK, Antonio  and  ORDONEZ MAYGUA, Javier. Progesterone as a forecasting factor for threats of abortion. Gac Med Bol [online]. 2009, vol.32, n.2, pp.11-16. ISSN 1012-2966.

Progesterone is one of the most important hormones for pregnancy continuity, and during the first nine weeks is almost of exclusive formation by the luteus body. Its deficiency is a probable cause of hemorrhage of the first half, whose low concentrations are associated to abortion threat and/or abortion, during growth periods lower than nine weeks. The certainty diagnosis for threat of abortion on patients with a menstrual delay lower than seven days becomes difficult since the ultrasound does not show definite information in most cases, and because the Beta-HGC, in case it is positive, only reports the presence of a gestation without any additional information about its state; thus, the determination of serum progesterone is suggested as a possible forecaster on such patients. A prospective longitudinal, correlational, laboratorial, and comparative study was carried out between two groups, distributed on patients with and without abortion threat of spontaneous start; expectant women with pregnancy periods lower than nine weeks, and placentary concentrations of progesterone were determined, observing that patients with high progesterone levels showed normal pregnancy progression once the threat event had been overcome; and it was similarly shown on expectant women without abortion threat, as opposed to patients with low progesterone levels whose pregnancy resulted in abortion. Later, patients with no complications during research time were included. Therefore, it can be concluded that determinations of progesterone on patients with gestation period lower than nine weeks can be useful as forecasters during the evolution of pregnancies, and on those who show low concentrations, the usefulness of progesterone supplements.

Keywords : Concentration of Progesterone; Abortion threat.

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