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vol.30 issue2COMPARACION DE DOS METODOS SEROLOGICOS PARA EL DIAGNOSTICO DE TOXOPLASMOSISSINDROME METABOLICO EN DOS CONSULTORIOS DE MEDICINA FAMILIAR, POLICLINICO 32, CAJA NACIONAL DE SALUD, COCHABAMBA author indexsubject indexarticles search
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Gaceta Médica Boliviana

Print version ISSN 1012-2966On-line version ISSN 2227-3662

Abstract

ESPINOZA DAVILA, Elvy  and  AGUILAR ESCOBAR, Jimena. WARFARINA Y ASPIRINA EN PACIENTES CON PATOLOGÍA CARDIACA EN EL HOSPITAL OBRERO N° 2 DE LA CAJA NACIONAL DE SALUD. Gac Med Bol [online]. 2007, vol.30, n.2, pp.15-17. ISSN 1012-2966.

Drugs with anticoagulant and platelet antiagregant effect are a fundamental component of the prophylactic management for patients with heart pathology. Their effectiveness has been shown clearly in secondary prevention of brain ischemic stroke. The objective of this work it was to describe and compare the prophylaxis effectiveness and complications of warfarina vs aspirin treatment in patients with heart pathology that attended to cardiology' external consultation at HO N° 2 of the CNS from January 2001 to january 2003. The universe was conformed by 350 patients, the sample with 152 patients than fulfilled inclusión criteria (indication of anticoagulation and antiagregation, treatment beginnig at same time of study's periodo, periodic clinical and laboratorial controls INR/TP and other diagnostic support tests. The results obtained were: 40 casos (26.31%) recevied prophylaxis with warfarina with variable and singular dose, 62 cases (40.78%) with 100 mgr of aspirin and 50 cases (32.89 %) with both. 24 cases presented complications due to overanticoagulatión or subanticoagulation, 12 cases with combineed therapy , warfarina 6 cases y aspirin 6 cases. The most often complications were: CVI, high digestive haemorrage. Anticoagulant prophilactic theraphy was eficace in most cases. Most frequent complications were in combined prophylactic groups, ischemic and haemorragic type.

Keywords : Warfarine; aspírine; INR; Time of protrombine.

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