Abstract

DE PARDO GHETTI, Evelin M.; MONROY DELGADILLO, Manuel  and  GUTIERREZ, José. SÍNDROME URÉMICO HEMOLÍTICO EN NIÑOS  EN H.M.I.G.U.. Gac Med Bol [online]. 2006, vol.29, n.2, pp.11-15. ISSN 1012-2966.

The hemolytic uremic syndrome (HUS) described in 1955, is defined as a sudden development of hemolytic microangiophatyc anemia on a previously health person, which is associated to thrombocytopenia and renal failure, with signs and symptoms of multiparenquimatosic insult, especially brain, reins and digestive tube. Ninety percent of children which have HUS, have one diarrheic episode. Most cases are caused by verotoxin releaser E. coli frequently by 0157:H7 group. The aim of present work was to report HUS D+ in children identifying and analyzing its development in our enviroment through causal germen Identification, mentioning the signs and symptoms , and looking the evolution, complications and prognostic of this pathology. The study was developed during one year at Hospital Materno Infantil Germán Urquidi and the Clínica del Niño from Cochabamba. The work was done by clinical history revision. Coproculture were negatives for 100%, but copro parasitological studies reported E. histolytica in all, one had chilomastic mesnilii, and other was positive to rotavirus(+). The most frequent alarm signs during prodromic period were fever higher to 39o, leucocytosis. The age was under 2 years old, Diagnostics criterio present along 100% of cases were anemia, and acute renal failure. Thrombocytopenia was in 80% of cases. 60% presented severe neurological symptoms and 80% required dialyses.

Keywords : Uremic Hemolytic Syndrome; micro angiopathic anemia; Thrombocytopenia; Children; Acute renal failure.

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