Abstract

CASTANETA, Grover; HUAYHUA-LLUSCO, Aleyda; TARQUI, Santiago  and  GUTIERREZ, Abel F.. Characterization of terpenoids from pseudognaphalium gaudichaudianum (dc) anderb, wira-wira by gc/ms, active principles with possible use in COVID-19 infection prevention. Rev. Bol. Quim [online]. 2022, vol.39, n.1, pp.19-25. ISSN 0250-5460.  https://doi.org/10.34098/2078-3949.39.1.3.

Pseudognaphalium gaudichaudianum (DC.) Anderb., (Asteraceae) is a small herbaceous plant that grows in the heights and in mountainous places. Known by the vernacular name “Wira Wira'', it is well reputed in traditional medicine by aymara communities to treat respiratory diseases like cough, common cold, bronchitis, and pneumonia in the highlands of Bolivia. Due of its expectorant properties, P. gaudichaudianum has been proposed as a phytodrug to prevent infection by COVID-19, in infusions and vaporization. In this study, the terpenoids from its essential oil were characterized by Gas Chromatography Coupled to Mass Spectrometry (GC/MS). The analysis showed the presence of 1 monoterpenoid, 11 sesquiterpenoids, 2 diterpenoids and 4 minor unidentified compounds. The major compounds identified were β-Eudesmene (16.35%), Rosifoliol (15.29%), Guaia 1(10), 11-diene (15.20%), Guaia 6,9 diene (14.46%), α-Pinene (11.32%) and α-Guaiene (6,16%).

Keywords : α-Pinene; Asteraceae; Covid-19; Essential oil; Terpenoids; Wira-wira.

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