Abstract

IBIETA JIMENEZ, Gabriela et al. Synthesis of the new 4’-hydroxy-3’-(3-methyl-2-butenyl)chalcone by microwave-assisted condensation of 4-hydroxy-3-(3’-methyl-2’-butenyl) acetophenone isolated from senecio graveolens and benzaldehyde. Rev. Bol. Quim [online]. 2017, vol.34, n.3, pp.89-103. ISSN 0250-5460.

In this article we report the synthesis of a new chalcone, 4’-hydroxy-3’-(3-methyl-2-butenyl)chalcone 2, from the organic condensation assisted by microwave irradiation of benzaldehyde and 4-hydroxy-3-(3-methyl-2-butenyl)acetophenone 1, the latter isolated from Senecio graveolens. Compound 2, being of synthetic origin has not been so far isolated from natural sources. Structures were established by modern NMR techniques.

Keywords : 4-Hydroxy-3-(3-methyl-2-butenyl)acetophenone; Benzaldehyde; 4’-hydroxy-3’-(3-methyl-2-butenyl)chalcone; Microwave-assisted Synthesis; Irradiation; Green Chemistry; NMR; Senecio graveolens; Asteraceae.

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