Abstract

PARRA LIZARAZU*, Carla; QUIROGA SELAEZ, Gabriela  and  GIMENEZ TURBA, Alberto. Selection of filamentous fungi capable of biotransforming the compound 2-phenylquinoline. Rev. Bol. Quim [online]. 2016, vol.33, n.4, pp.142-148. ISSN 0250-5460.

Abstract Eighty strains, previously preserved by lyophilization, from the fungi collection of the Instituto de Investigaciones Fármaco Bioquimicas-IIFB, part of the Major San Andrés University, were activated. Ten strains were preselected based on its ability to show development in an Agar médium with 2-phenylquinoline as the only substrate. To evalúate the biotransformation process of the alkaloid, batch cultures were established in two different media; Sabouraud broth and Basal Médium for fungi. Analysis by thin layer chromatography allowed to select 6 strains which showed the formation of different products. Out of all the strains analyzed, strain 114QD was the one that showed products of interest in both media.

Keywords : Biotransformation; 2-phenylquinoline; fílamentous fungí.

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