Abstract

BRAVO, José A; VILA, José L; DEPARTMENT OF CHEMISTRY, LABORATORIO DE SINTESIS Y HEMISINTESIS, INSTITUTO DE INVESTIGACIONES EN PRODUCTOS NATURALES IIPN. Department of Chemistry, Laboratorio de Síntesis y Hemisíntesis, Instituto de Investigaciones en Productos Naturales IIPN  and  UNIVERSIDAD MAYOR DE SAN ANDRES UMSA. Mechanistic views of stereoselective synthesis of tri-and tetra-substituted alkenes, part II; the organic chemistry notebook series, a didacticalapproach, N° 4. Rev. Bol. Quim [online]. 2015, vol.32, n.1, pp.15-23. ISSN 0250-5460.

This is the complementing part of the previously published: "Mechanistic views of stereoselective synthesis of tri-and tetra-substituted alkenes, part I; The Organic Chemistry Notebook Series, a Didactical Approach, N° 3". As underlined in three previous papers the presentation of synthesis works in a verbal and graphical succinct manner, needs a didactical approach. Isomerically pure tri- and tetra-substituted alkenes are difficult to obtain as shown in several publications. We used a series of reactions to synthesize tri- and tetra-substituted alkenes as reviewed by W. Carruthers, and we have proposed didactical and mechanistic views for the reviewed reactions. These two latest approaches are included in the synthetic methods reviewed by W. Carruthers with respect to the "Formation of carbon-carbon double bonds". Spanish title: Vistas mecanísticas de síntesis estereoselectivas de alquenos tri y tetrasubstituidos, Parte II, Serie: El cuaderno de notas de química orgánica, un enfoque didáctico, N°4.

Keywords : Organic Chemistry; Stereoselective synthesis; Alkenes; Addition reaction; Mechanisms of Reactions.

        · text in Spanish     · Spanish ( pdf )