Abstract

LAYTON TOVAR, Cristian F; CUEVAS YANEZ, Erick; VELASCO MONTEJO, Bayardo E  and  MENDIETA ZERON, Hugo. HIGH SUSCEPTIBILITY OF CANDIDA ALBICANS ATCC 10231 TO TETRAHYDROFURANOSYL-1,2,3-TRIAZOLES OBTAINED BY CLICK CHEMISTRY. Rev. Bol. Quim [online]. 2014, vol.31, n.1, pp.15-21. ISSN 0250-5460.

ABSTRACT Tetrahydrofuranosyl-1,2,3-triazoles, synthesized by "Click chemistry", were tested as novel antifungal compounds. The results show a remarkable activity against Candida albicans ATCC 10231 expressed in a high MIC50 and MIC90 compared to traditional antifungals such as fluconazole.  

Keywords : antimycotic effect; Click Chemistry; triazoles.

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