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Revista Boliviana de Química

On-line version ISSN 0250-5460

Abstract

TARQUI TARQUI, Santiago; FLORES SEGURA, Yonny  and  ALMANZA VEGA, Giovanna R.. POLYOXYGENATED FLAVONOIDS FROM BACCHARIS PENTLANDII. Rev. Bol. Quim [online]. 2012, vol.29, n.1, pp.10-14. ISSN 0250-5460.

ABSTRACT Three highly oxygenated flavonoids were isolated from the leaves of the medicinal plant Baccharis pentlandii commonly known as "Chilca clara" Mayu chilca or simply "Chilca". Flavonoids were identified as: 5,4'dihydroxy-6,7,8,3 -tetramethoxyflavone 8-Methoxycirsilineol (1), 5,4'-dihydroxy-6,7,8-trimethoxyflavone Xanthomicrol (2) and 5,3',4'-trihydroxy-6,7,8-trimethoxyflavone Sideritoflavone (3) by spectroscopic methods. The compounds are the major chemical constituents in the plant and they have proved to be cytotoxic as well as apoptotic substances giving thus the species a potential interest against cancer.

Keywords : Baccharis pentlandii; poly-oxygenated flavonoids; 8-methoxycirsilineol; xanthomicrol; sideritoflavone; Bolivian Medicinal Plants.

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