Abstract

BRAVO, José A; VILA, José; PENARRIETA, Mauricio  and  MOLLINEDO, Patricia. STEREOCHEMICAL ANALYSIS OF NATURAL PRODUCTS BY NMR THE J-BASED APPROACH, A SHORT REVIEW. Rev. Bol. Quim [online]. 2010, vol.27, n.2, pp.107-118. ISSN 0250-5460.

This is a short review on some available information regarding recent advances in the application of new approaches to the establishment of the close relationship conformation/configuration in flexible systems. These are usually characterized by containing a number of stereogenic sites and it became interesting to evaluate how the new tools could help in defining configurations. The new developments are particularly suitable for the analysis of natural products.  Indeed, we are here circumscribed only to the so-called “J-based approach”

Keywords : Stereochemistry; flexible macrocyciclic; conformation; configuration; natural products; NMR; homonuclear coupling; hetereonuclear coupling; J-based approach.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )