Abstract

VALDIVIA, Ana C; MOLLINEDO, Patricia; VILASECA, Antonio  and  STERNER, Olov. Prenylated protocatechuic acid derivatives with anti-oxidant activity from Piper heterophyllum. Rev. Bol. Quim [online]. 2009, vol.26, n.2, pp.83-89. ISSN 0250-5460.

Two new protocatechuic acid derivatives, arieianoic acid (1) and arieianol (2), were isolated from the aerial parts of Piper heterophyllum Ruíz & Pavon and their structures were determined by spectroscopic techniques. From 1, the semi-synthetic derivatives 3-8 were prepared. The antioxidant activity of the natural and semi-synthetic derivatives were evaluated using the DPPH assay

Keywords : Piper heterophyllum; prenylated protocatechuic acid; diester; tetraol; dialdehyde; chromane; antioxidant activity.