Abstract

MELGAREJO, Marcela; STERNER, Olov; VILA CASTRO, José  and  MOLLINEDO, Patricia. MORE INVESTIGATIONS IN POTENT ACTIVITY AND RELATIONSHIP STRUCTURE OF THE LICHEN ANTIBIOTIC (+)-USNIC ACID AND ITS DERIVATE DIBENZOYLUSNIC ACID. Rev. Bol. Quim [online]. 2008, vol.25, n.1, pp.24-29. ISSN 0250-5460.

By reacting R-(+)-usnic acid (1) with benzoyl chloride in presence of pyridine gave the dibenzoylusnic acid (2). The antibacterial activity and relationship structure of acid usnic an old lichen drug and its derivate dibenzoylusnic acid was studied against nine ATCC bacteria and one bacterium clinical isolate.

Keywords : lichens; usnic acid; dibenzoylusnic acid; antibacterial activity; relationship structure; ditch diffusion method.

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