Abstract

BALLESTEROS, Fátima; SEJAS, Magali; HERBAS, Adelina  and  CARPENTIER, Ivon. SINDROME METABÓLICO Y SU RELACIÓN CON ÁCIDOS GRASOS OMEGA 3. Rev. Bol. Quim [online]. 2007, vol.24, n.1, pp.58-63. ISSN 0250-5460.

ABSTRACT In the present work has been studied the relationship of the metabolic syndrome with the level of fatty acids ω3 (omega 3) and ω6 (omega 6) present in the sanguine plasma. The studied population comprised 96 patients of the Caja Nacional of Health (CNS) of the city of Cochabamba-Bolivia with ages between the 18 and 65 years, of which 50% present Metabolic Syndrome. For the relationship studies have been taken 50% of the population's with Metabolic Syndrome (24 patients) and 50% without Metabolic Syndrome (24 patients). The clinical analyses have been based on enzymatic methods and those of composition in fatty acids in plasma, in Gas Chromatography methods. The ω6 fatty acids content in plasma don't show significant differences between both groups of patients (with and without Metabolic Syndrome). On the other hand, the study of the ω3 fatty acids content showed a bigger proportion of EPA (eicosapentaenoic acid), of DHA (docosahexanoic acid) and of the sum of ω3 acids in people without Metabolic Syndrome; although a smaller ω6/ω3 relationship among fatty acids was determined (with a value of 25.8938) in people that didn't present Metabolic Syndrome with regard to those that present it, the same one surpasses the limits settled down by the FAO (2002, with a maximum value of ω6/ω3 = 10).  Also, an associated inverse relationship of the DHA acid with the diastolic pressure, abdominal obesity, glycaemia and triglycerides was found, as well as the sum of fatty acids ω3 with an inversely associated relationship with abdominal obesity. An association can be settled down among the presence of fatty acids ω3 in plasma and the factors of the Metabolic Syndrome; consequently, an appropriate intake of these fatty acids could prevent the presence of this Syndrome

Keywords : Metabolic Syndrome; Fatty omega 3 and omega 6 acids; Eicosapentaenoico acid (EPA); Docosahexanoic acid (DHA).

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